![]() In patients who were treated with radiotherapy the survival was potentially predictable with age, race and p53, but available research on other markers is limited. Other prognostic features of clinical or PSA-associated progression include age, IGF-1, p27, and Ki-67. ![]() Progression can also be predicted with biological markers (E-cadherin, microvessel density, and aneuploidy) with high level of significance. Progression-associated features include Gleason score, stage, and capsular invasion, but PSA is also highly significant. ![]() Also the origins from the transitional zone, p53 status in cancer tissue, stage, and aneuploidy have shown prognostic significance. Gleason score, tumour volume, surgical margins and Ki-67 index have the most significant prognosticators. Prognostic factors in organ confined prostate cancer will reflect survival after surgical radical prostatectomy.
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